Place in the book. Why the one who knows should not be disturbed by the ignorant — because he holds the cosmic order in mind. The discipline of desire (φυσιολογία), with a secondary of assent.
The ignorant do not disturb the knowing. A rhetorical question: "why do unskilled and ignorant souls (ἄτεχνοι, ἀμαθεῖς) disturb (συγχέουσιν) the skilled and knowing one (ἔντεχνον, ἐπιστήμονα)?" The implication: they should not — knowledge is armour against others' confusion.
What the knowing soul is. EXERCISEThe soul "that knows beginning and end" (ἀρχὴν καὶ τέλος) — grasping the Whole; that knows TERM"the reason which pervades all substance" (δι' ὅλης τῆς οὐσίας διήκοντα λόγον) — the cosmic Logos; and DOGMAthat "through all time by fixed periods administers the universe" (κατὰ περιόδους τεταγμένας) — the cycles of the cosmos (ἐκπύρωσις / παλιγγενεσία). It is DOGMAthe one Logos pervading all and governing it in revolutions.
The therapy. Anxiety is born of short-sightedness — seeing only the particular. Knowledge of the ἀρχή / τέλος / λόγος / periods gives the scale on which the opinions of the ignorant are nothing: one who sees the particular against the Whole cannot be shaken. φυσιολογία as the armour of imperturbability.
Discipline and parallels. The principal discipline is desire (contemplating the Logos and the cycles → imperturbability); the secondary is assent (not being disturbed by others' confusion). Parallels: Med. 6.37 ("the one who has seen the present has seen all"); 05-13; 2.14 (the cycles and the levelling of durations).